Lecture on genome mining of filamentous fungi

报告题目:Uncovering the Biosynthetic Secrets of Filamentous Fungi
报告人:Yi Tang,
         Associate Professor   
          Department of Chemical and Biomolecular Engineering,
          University of California,
          Los Angeles, CA

报告时间:4月20日 上午9:30
报告地点:徐汇校区科学馆112室
组织单位:微生物代谢实验室
abstract:   In this talk, I will present recent progresses made in my  lab towards the reconstitution, characterization and engineering of fungal secondary metabolic pathways. We have established robust  heterologous platforms, such as E. coli and S. cerevisiae, for the expression of fungal megasynthases. Megasynthases that will be discussed include polyketide synthases (PKS), nonribosomal synthetases  (NRPS) and PKS-NRPS hybrids. These microbial hosts can be powerful  tools for genome mining of filamentous fungi.

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